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Organic chemistry – multistep synthesis

Organic chemistry – multistep synthesis

Title

Please select a pharmaceutical drug (legal), whose synthesis is at least 6 steps. Do not choose from “biologics”, which means antibodies, dna, peptides that are produced from cells or other biological sources. Please report on the following

The report should have the following sections:

Abstract (75 word limit),  

Introduction discuss history of disease that the drug addresses and how people are affected, strategies used to combat disease that existed prior to the drug you are reporting on

Results: how the drug was discovered, who is the commercial vendor and yearly sales, its biological mode of action, side effects,

Preparation  includes your synthetic scheme, and separate schemes for  mechanisms of the steps that use mechanisms we have learned in class. Your report must contain at least 1 mechanistic scheme.  You are encouraged to use any other figures, charts, or tables that help support your discussion. All schemes must be drawn with chemdraw (available to Hunter students) or similar software. Hand drawn schemes will not be accepted.

Conclusions – summarize findings and outlook (do we need new drugs? What is the problem with this drug).

References.

The references will need to include the journal article where the synthesis was originally reported and where the compound was originally discovered, and any other relevant references that you cite. The references should follow the format: Author names, “title”, Year, volume, first page – last page.

Please submit as .pdf.  This report has a 3 page limit, including title and references.

 

NOTE :

I want the paper structured like this with the bold subheadings.

Choose a simple drug that is at least 6 steps because we only got up to chapter 20 in the WILEY david klein textbook (organic chemistry), its available on b-ok.org